Image by Flickr user rogersmj Pane e Vino also has a nice closed in courtyard space.
The mussels are one of my favorite dishes there, and one of the few in town that are prepared in a red sauce. The place is certainly one of Charleston's best Italian restaurants, provided you're not overly demanding of prompt service. That can be the Achilles' heel of this small quaint eatery at 17 Warren Street.
Read more about the restaurant on our Pane e Vino topic page.