I've always been partial to the beer lineup that Wren brings in. Q on Bay often gives them a run for the money though.
Let's face it, in Beaufort there are two types: those that know every bar in downtown Beaufort, and those that don't really care.
But if you're new to town then be sure to check out Lowcountry Weekly's guide to bars and drinking spots on Bay Street and a few just off Bay; read it here.
Now they just need to do one that includes water holes a bit further out — though back in 2010 they did profile Beaufort's many sports bars.